OpenSWATH 2.5正式版发布

OpenSWATH工作流支持DIA或SWATH蛋白质组数据的数据分析，历时两年OpenSWATH2.5正式版在github上已经放出。本次更新有很多改进：

常规更新:

support for RNA mass spectrometry
TMT16plex support for IsobaricAnalyzer
improved MsStats/MsStatsTMT output support
extended MaxQuant-compatible mzXML support (via FileConverter)
QualityControl Workflow (all in the QC folder)
OpenMS and pyOpenMS support for oligonucleotides
OpenSWATH support for ion mobility extraction and scoring
OpenSWATH support for metabolite assay library building through SIRIUS (and metabolite extraction and scoring)
OpenSWATH support for PRM
TOPPAS improvements
fixes to PeptideIndexer for X!Tandem special cutting rules and ambiguous amino acids
support for HDF5
support for hyperfine isotopic distributions (through IsoSpec)
JSON support
speed improvements (loading/storing files, handling peptide sequences)
support for VS2019 and GCC 9.1
support for outlier removal in IDPosteriorErrorProbability
reduced memory footprint of FeatureFinderIdentification through batch processing

新增工具:

Epifany — Runs a Bayesian protein inference (UTIL)
FeatureFinderMetaboIdent — Detects features in MS1 data based on metabolite identifications (UTIL)
GNPSExport — Tool to export consensus features into MGF format (TOPP)
NucleicAcidSearchEngine — Annotate nucleic acid identifications to MS/MS spectra (UTIL)
ProteomicsLFQ — A standard proteomics LFQ pipeline (TOPP) (experimental)
QualityControl — Computes various QC metrics from many possible input files (only the consensusXML is required). The more optional files you provide, the more metrics you get (TOPP)
RNAMassCalculator — Calculates masses and mass-to-charge ratios of RNA sequences (UTIL)
MapAlignerTreeGuided — Aligns maps through hierarchical clustering based on distances computed between shared IDs.

Omics - Hunter