Omics - Hunter

OpenSWATH 2.5正式版发布

OpenSWATH工作流支持DIA或SWATH蛋白质组数据的数据分析,历时两年OpenSWATH2.5正式版在github上已经放出。本次更新有很多改进:

常规更新:

  • support for RNA mass spectrometry
  • TMT16plex support for IsobaricAnalyzer
  • improved MsStats/MsStatsTMT output support
  • extended MaxQuant-compatible mzXML support (via FileConverter)
  • QualityControl Workflow (all in the QC folder)
  • OpenMS and pyOpenMS support for oligonucleotides
  • OpenSWATH support for ion mobility extraction and scoring
  • OpenSWATH support for metabolite assay library building through SIRIUS (and metabolite extraction and scoring)
  • OpenSWATH support for PRM
  • TOPPAS improvements
  • fixes to PeptideIndexer for X!Tandem special cutting rules and ambiguous amino acids
  • support for HDF5
  • support for hyperfine isotopic distributions (through IsoSpec)
  • JSON support
  • speed improvements (loading/storing files, handling peptide sequences)
  • support for VS2019 and GCC 9.1
  • support for outlier removal in IDPosteriorErrorProbability
  • reduced memory footprint of FeatureFinderIdentification through batch processing

新增工具:

  • Epifany — Runs a Bayesian protein inference (UTIL)
  • FeatureFinderMetaboIdent — Detects features in MS1 data based on metabolite identifications (UTIL)
  • GNPSExport — Tool to export consensus features into MGF format (TOPP)
  • NucleicAcidSearchEngine — Annotate nucleic acid identifications to MS/MS spectra (UTIL)
  • ProteomicsLFQ — A standard proteomics LFQ pipeline (TOPP) (experimental)
  • QualityControl — Computes various QC metrics from many possible input files (only the consensusXML is required). The more optional files you provide, the more metrics you get (TOPP)
  • RNAMassCalculator — Calculates masses and mass-to-charge ratios of RNA sequences (UTIL)
  • MapAlignerTreeGuided — Aligns maps through hierarchical clustering based on distances computed between shared IDs.

下载地址:

Win:下载

Mac:下载

Debian/Ubantu:下载

源码:下载

另外可以到此处下载更新/开发版:下载

参考资料:

1.http://openswath.org/en/latest/

2.https://zhuanlan.zhihu.com/p/37309267

3.https://github.com/OpenMS/OpenMS/releases


作者:陈浩


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2 评论

  1. 陈浩

    2023/4/5 在 11:50

    OpenMS 2.8已经发布,下载:https://github.com/OpenMS/OpenMS/releases/download/Release2.8.0/OpenMS-2.8.0-Win64.exe

  2. 陈浩

    2020/12/20 在 23:42

    OpenMS 2.6.0已经发布:https://github.com/OpenMS/OpenMS/releases

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