本篇总结了蛋白质组常用缩略词名词:
DIA | Data independent acquisition |
DDA | Data dependent acquisition |
TMT | Tandem Mass Tag |
iTRAQ | isobaric tags for relative and absolute quantitation |
SILAC | Stable Isotope Labeling with Amino acids in Cell culture |
PRM | Parallel Reaction Monitoring |
MRM | multiple reaction monitoring |
SRM | selected reaction monitoring |
SWATH | Sequential Window Acquisition of all THeoretical Mass Spectra |
TQS | triple quadrupole system |
Label Free | Label Free Quantitative Proteomics |
LFQ | Label Free Quantitative |
PTM | Post-translational modification |
PPI | protein-protein interaction |
FDR | false discovery rate |
MS | mass spectrometry |
SILAC | stable isotope labeling of amino acids in cell culture |
HPLC | high performance liquid chromatography |
PSM | peptide-to-spectrum match / peptide-spectrum matches |
CPTAC | Clinical Proteomic Technology Assessment for Cancer Network |
UPS | Universal Proteomics Standard 1 |
FP | false positives |
FN | false negatives |
TP | true positives |
TN | true negatives |
PPV | positive predictive value |
FC | fold change |
ROC | receiver operating curve |
pAUC | partial area under the curve |
rpAUC | relative partial area under the curve |
DE | differential expression |
DEP | differential expression proteins |